Journal of Autoimmune and Systemic Diseases
Editor in Chief: Kota V. Ramana
- About Journal
- Focus & Scope
- Editor in Chief
- Editorial Board
- Submit Manuscript
- Article Processing Charges
Discoid Lupus ErythematosusLuciano Zogbi1*
1Department of surgery, Federal University do Rio Grande (FURG), Brazil
*Corresponding author: Luciano Zogbi, Department of Surgery, Federal University of Rio Grande (FURG), Rua Viconde de Paranagué 102. Faculdade de Medicina – 4º andar da área acadêmica, Rio Grande, RS, Brazil- 96203-900, Tel: 55 53 32338800; E-mail: firstname.lastname@example.org
Received: December 23, 2017; Accepted: December 24, 2017; Published: December 31, 2017
Copyright: ©2017 Zogbi L. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citation: Zogbi L (2017) Discoid lupus erythematosus. J Autoimmune Systemic Dis 1(1): 100005.
A 24-year-old male Caucasian presented with an erythematous malar lesion. The lesion had irregular and slightly elevated borders, with somewhat indurated plaques covered by a well-formed adherent scale in the center and with similar but smaller satellite lesions. An incisional biopsy was performed, revealing epidermal atrophy, degeneration of the basal layer and mononuclear infiltration of the dermis. These features were consistent with classic findings of the autoimmune disease discoid lupus erythematosus (DLE). The plaques of DLE tend to expand slowly with active inflammation at the periphery and then heal, leaving depressed central scars, atrophy, telangiectasias, and hyperpigmentation and/or hypopigmentation. DLE most often involves the face, neck, and scalp. The patient underwent clinical treatment with improvement of the lesions. Though he did not meet criteria for systemic lupus erythematosus (SLE), progression to SLE may occur in up to 28 percent of patients initially presenting with DLE.